Bio-equivalent doses of recombinant HCG and recombinant LH during ovarian stimulation result in similar oestradiol output: a randomized controlled study
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چکیده
منابع مشابه
I-36: The Role of LH in Controlled Ovarian Stimulation
It is known that the follicular selection and final stages of follicular maturation are equal if not more dependent on low circulating levels of LH.In addition to stimulating production of thecal androgens as substrate for estrogen synthesis, LH stimulates granulose cell via LH receptors induced by FSH and estrogen in larger but not smaller follicles. The data from numerous assisted reproductio...
متن کاملEffects of recombinant LH supplementation to recombinant FSH during induced ovarian stimulation in the GnRH-agonist protocol: a matched case-control study
BACKGROUND Some studies have suggested that the suppression of endogenous LH secretion does not seem to affect the majority of patients who are undergoing assisted reproduction and stimulation with recombinant FSH (r-FSH). Other studies have indicated that a group of normogonadotrophic women down-regulated and stimulated with pure FSH preparations may experience low LH concentrations that compr...
متن کاملThe effect of recombinant LH on embryo quality: a randomized controlled trial in women with poor ovarian reserve.
BACKGROUND Poor ovarian response is a common clinical problem, affecting up to 26% of IVF cycles. For these women, addition of recombinant luteinizing hormone (rLH) to ovarian hyperstimulation with recombinant FSH has a beneficial effect on ongoing pregnancy rates, but its effect on the yield of top-quality embryos is unknown. METHODS We conducted a randomized controlled trial in women expect...
متن کاملA prospective, randomized, controlled, double-blind, double-dummy comparison of recombinant and urinary HCG for inducing oocyte maturation and follicular luteinization in ovarian stimulation.
A randomized, controlled, double-blind, double-dummy, phase III clinical trial was conducted in 84 women to compare the efficacy of a s.c. injection of 250 microg recombinant human chorionic gonadotrophin (rHCG; Ovidrel) to an i.m. injection of 5000 IU urinary HCG (uHCG; Profasi) in inducing folliculogenesis, resumption of oocyte meiosis and luteinization after ovulation induction with recombin...
متن کاملSuppression of LH during ovarian stimulation: effects differ in cycles stimulated with purified urinary FSH and recombinant FSH.
There has been much debate about the role of luteinizing hormone (LH) during follicle stimulating hormone (FSH)-treated ovarian stimulation for assisted reproduction, where the endogenous LH is suppressed using a gonadotrophin-releasing hormone analogue. The requirement for LH in oestradiol biosynthesis is established, but other effects of 'insufficiency' are less clear, and little attention ha...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2017
ISSN: 1472-6483
DOI: 10.1016/j.rbmo.2017.05.001